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KMID : 1007520150240020705
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Food Science and Biotechnology
2015 Volume.24 No. 2 p.705 ~ p.715
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Dietary Supplementation with a Fermented Barley and Soybean Mixture Attenuates UVB-induced Skin Aging and Dehydration in Hairless Mouse Skin
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Kwon Oh-Wook
Ramu Venkatesan
Do Moon-Ho
Ji Eun-Hee
Cho Dong-Woon
Lee Ki-Won
Kim Sun-Yeou
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Abstract
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This study evaluated the protective effects of dietary supplementation with a fermented barley and soybean mixture (BS) on ultraviolet (UV) B-induced photoaging in hairless mice. Skin aging-related parameters and protein levels related to skin wrinkles and moisturization in mice were analyzed. The BS reduced wrinkle formation, skin thickening, transepidermal water loss, and matrix metalloproteinases- 1 expression in skin. Skin hydration and pH were increased in the BS group. BS attenuated filaggrin expression as well as free amino acid and glycerol production. BS increased superoxide dismutase activity as well as increased expression of nuclear factor (erythroidderived 2)-like 2, procollagen type-I, and decreased erythema. These results suggest that BS protects against photoaging induced by UVB in vivo, indicating the potential of such mixtures as anti-photoaging dietary supplementation.
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KEYWORD
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photoaging, skin hydration, hairless mice, ultraviolet B, fermented barley and soybean mixture (BS)
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